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Avoid coadministration of pazopanib with solid CYP3A4 inhibitors if possible; if must coadminister, minimize pazopanib dose to 400 mg/dayMinor (one)dasatinib and pazopanib equally improve QTc interval. Minor/Significance Unknown.Serious - Use Alternative (one)aluminum hydroxide/magnesium trisilicate will minimize the level or effect of pazopanib by